Nāpili-Honokōwai is a census-designated place (CDP) in Maui County, Hawaiʻi, United States. The population was 7,261 at the 2010 census.

Nāpili-Honokōwai is located at 20°58′1″N 156°40′14″W (20.966949, -156.670672),[2] between the communities of Kapalua to the north and Kaanapali to the south. It consists of three separate neighborhoods (from north to south) Nāpili, Kahana, and Honokōwai.

According to the United States Census Bureau, the CDP has a total area of 4.3 square miles (11.1 km2), of which 2.6 square miles (6.8 km2) is land and 1.7 square miles (4.3 km2), or 38.35%, is water.